A study to assess the impact of implementing the Five Mandatory Steps of Safe Medication Practice, along with video-based reinforcement, on improving nursesβ medication administration compliance.
Five Medication Mandates: A Video-Enabled Quality Improvement Initiative
- World Health Organization. Medication Without Harm: Global Patient Safety Challenge. Geneva: World Health Organization; 2017.
- World Health Organization. Global Patient Safety Action Plan 2021β2030. Geneva: World Health Organization.
- National Accreditation Board for Hospitals & Healthcare Providers (NABH). Hospital Accreditation Standards, 5th Edition. Quality Council of India.
- Institute of Medicine. Preventing Medication Errors. Washington, DC: National Academies Press; 2007.
- Institute for Safe Medication Practices (ISMP). Principles of Safe Medication Practices.
Initiative
Objectives
- To assess baseline compliance of nurses with the Five Medication Mandates prior to intervention.
- To implement structured training and video-based reinforcement for all nursing staff within four months.
- To improve compliance with the Five Medication Mandates from 85.6% to 90.8% through post-intervention audits.
- To reduce medication administration errors by strengthening adherence to standardi
Methodology
Study Design
Prospective nurse-led Quality Improvement initiative.
Setting
Inpatient wards of S. L. Raheja Hospital, A Fortis Associate, Mumbai.
Study Population
Registered nurses involved in medication administration.
Sample
Medication administration practices observed through pre- and post-intervention compliance audits conducted among nursing staff.
Study Duration
October 2025 to February 2026.
Intervention
The Five Medication Mandates were standardized through structured training, bedside demonstrations, display of visual reminder posters, and video-based reinforcement. Nursing supervisors and educators provided continuous coaching, while compliance was reinforced during routine medication rounds.
Data Collection
Compliance was assessed using a standardized observational audit checklist before and after implementation. Medication administration error data were obtained from the hospital incident reporting system.
Outcome Measures
Overall compliance with the Five Medication Mandates, compliance with each individual mandate, and the number of medication administration errors.
Data Analysis
Pre- and post-intervention audit findings and medication error trends were compared using descriptive statistics to evaluate the effectiveness of the intervention.
Results and Impact
The intervention was evaluated over a four-month period through pre- and post-implementation compliance audits and medication error monitoring. Overall compliance with the Five Medication Mandates improved from 85.6% at baseline to 90.8% post-intervention, achieving the project objective.
Compliance improved from 73% to 83% for carrying the patient file to the bedside, 74% to 83% for patient identification, and 90% to 99% for medication verification, while 100% compliance was maintained for bedside medication preparation and administration.
Medication administration errors reduced from 11 incidents (JulyβNovember 2025) to 1 incident (December 2025βFebruary 2026), with zero errors reported in January and February 2026.
The initiative standardized medication administration practices, strengthened documentation compliance, enhanced patient safety, improved staff accountability, and fostered a culture of continuous quality improvement. Video-based reinforcement proved to be an effective and sustainable strategy for maintaining consistent nursing practice.
Challenges & Critical Success Factors
Key Challenges
Key challenges included variation in existing medication administration practices, resistance to behavioural change, workload-related interruptions during medication rounds, and sustaining compliance following initial training. Ensuring consistent adherence across all nursing units required ongoing reinforcement and monitoring.
Critical Success Factors
Critical success factors included strong leadership support from Nursing Services, active involvement of Nursing Education and the Quality Department, structured competency-based training, video-based reinforcement, regular compliance audits, and timely feedback to frontline staff. Visual reminders displayed in clinical areas and continuous bedside coaching further strengthened adherence.
Leadership engagement, staff participation, and integration of the Five Medication Mandates into routine nursing workflows were instrumental in achieving sustained improvement.
Key Learnings
Standardizing medication administration through clearly defined mandatory practices, supported by continuous education and video-based reinforcement, significantly improved compliance and strengthened patient safety. Regular audits, leadership engagement, and timely feedback promoted sustained behavioural change and accountability among nursing staff.
Embedding the Five Medication Mandates into routine clinical practice enhanced documentation quality, reduced variation in practice, and supported continuous quality improvement. The initiative demonstrated that simple, structured, and scalable interventions can improve accreditation readiness by strengthening compliance with medication safety standards and fostering a culture of safe, reliable, and patient-centred care.